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Polynucleotides – salmon DNA

 

Vanaf €350,-

The polynucleotide treatment, also known as the salmon DNA treatment, focuses on improving skin quality from within. At Amsterdam Skin Clinic, we work with Rejuran, a treatment based on purified polynucleotides derived from salmon DNA.

Polynucleotides support processes in the skin involved in repair, hydration, elasticity and collagen production. As a result, your skin can gradually look firmer, smoother and fresher, without adding extra volume as a filler would.

Total price

Vanaf

€350,-

Treatment time

20-30 minutes

Effect

6-12 months

Sessies

3

Ask the doctor your questions and receive information.

What is a polynucleotide treatment?

A polynucleotide treatment uses purified DNA fragments derived from salmon sperm. Because these closely resemble human DNA, your body recognises them and they are safely absorbed. In practice, this is also known as a salmon DNA treatment, a more accessible name for the same technique.

Polynucleotides stimulate the skin to repair itself: they improve hydration, support collagen production and contribute to firmer, healthier skin. It is no surprise that these treatments have quickly become a global trend in aesthetic medicine.

Benefits of salmon DNA injections

A polynucleotide treatment not only provides support at a cellular level, but above all shows clear results in the skin. The most commonly experienced benefits are:

  • Collagen stimulation: firmer skin and improved elasticity
  • Intense hydration: the skin feels fuller and better nourished
  • More even skin tone: reduced dullness and minor irregularities
  • Healthy glow: a fresh and youthful appearance

The treatment can also be safely used on several areas, including the face, neck, décolleté and hands. This way, you target exactly the areas where signs of ageing often appear first.

Polynucleotides under the eyes

The skin around the eyes is thin and delicate, which means fine lines, dryness and loss of elasticity can appear sooner. Polynucleotides can be used to support skin quality in this area, without adding volume as a filler would.

Within the Rejuran range, Rejuran I is a variant specifically developed for the delicate skin around the eyes. The treatment focuses on improving skin texture, hydration and fine lines, so the eye area can gradually look fresher.

Polynucleotides may also be suitable in some cases for a tired appearance or dark circles. However, dark circles can have different causes. During the consultation, the doctor will therefore first assess whether Rejuran around the eyes suits your skin and wishes.

Which areas can be treated with polynucleotides?

The polynucleotide treatment is suitable for several areas where signs of ageing often appear first, such as:

  • Face: for more firmness, a fresh appearance and a natural glow
  • Eye area: to improve skin quality and hydration and soften fine lines
  • Neck and décolleté: to improve skin texture and elasticity
  • Hands: to improve skin quality and hydration for smoother, well-cared-for skin

Would you like to know which area is most suitable for you? At Amsterdam Skin Clinic, you can book a free consultation, where we look at your wishes together and, if appropriate, create a personal treatment plan. The consultation is completely free of obligation.

Polynucleotide treatment with Rejuran

At Amsterdam Skin Clinic, we work with Rejuran, a South Korean treatment based on purified polynucleotides (PN) derived from salmon DNA. Rejuran focuses on improving skin quality and is used to support hydration, elasticity and skin texture, among other things, without adding volume as a filler would.

The Rejuran range includes different variants for specific treatment areas. For example, Rejuran Healer is used for overall skin improvement, and Rejuran I for the thin, delicate skin around the eyes. During the consultation, the doctor will assess which treatment best suits your skin condition and wishes.

How a polynucleotide (salmon DNA) treatment works

A skinbooster treatment with salmon DNA consists of a few clear steps:

Free consultation

The treatment always starts with a free consultation at Amsterdam Skin Clinic. During this consultation, you discuss your wishes and expectations with the doctor. Your skin condition is assessed, followed by honest advice on the possibilities and the results you can expect. Of course, you are under no obligation to go ahead with the treatment after the consultation.

Preparing the treatment

On the day of the treatment, your skin is carefully cleansed and assessed. If desired, a numbing cream can be applied to make the treatment as comfortable as possible.

The treatment

Using a fine needle, the Rejuran solution is injected superficially into the skin. The polynucleotides stimulate the skin cells and activate the natural repair process. The treatment is quick and generally well tolerated.

Aftercare following polynucleotides

After the treatment, small bumps may be visible where the polynucleotides were injected. On the face, these usually disappear within 24 hours, while on the neck and décolleté this can often take 3 to 7 days. The result develops gradually in the weeks after the treatment: your skin becomes better hydrated and firmer, with a fresh, healthy appearance. For optimal and long-lasting results, we often recommend a course of several treatments.

What to do after a polynucleotide (salmon DNA) treatment?

Good aftercare helps you get the best results from your treatment. Keep the following in mind:

  • Massage: with Rejuran, intensive massage is not necessary (unlike some fillers and skinboosters). You may gently touch the skin during the first few days to relieve any sensitivity.
  • Avoid heat: stay out of saunas and sunbeds for the first 24 to 48 hours and limit sun exposure.
  • Rest: postpone strenuous activity or exercise for a while to limit swelling or bruising.
  • Recovery: redness, mild swelling or minor bruising usually disappear on their own within a few days.

After that, your skin is given time to respond to the polynucleotides. The effect builds up gradually: after a few weeks, your skin feels fresher, firmer and better hydrated.

How often is a polynucleotide treatment needed?

A polynucleotide (salmon DNA) treatment is not always a one-off session. For the best and longest-lasting results, the treatment is usually repeated 2 to 3 times. The exact number of treatments always depends on your skin condition and personal goals. During the free consultation, the doctor will discuss which treatment plan best suits your situation.

Book a free consultation

Curious whether a polynucleotide treatment with Rejuran is right for you? At Amsterdam Skin Clinic, we always start with a free consultation. During this consultation, we discuss your wishes and expectations, analyse your skin and give you honest advice on the possibilities and the results you can expect. This way, you know exactly where you stand before making a decision.

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FAQ

A salmon DNA treatment is another name for a polynucleotide treatment: purified DNA fragments derived from salmon. These are injected into the skin to support processes related to skin repair, hydration and collagen production. At Amsterdam Skin Clinic, we use Rejuran for this treatment.

The term “salmon sperm facial” is often used online and on social media for polynucleotide treatments. However, the treatment does not involve injecting salmon sperm directly into the skin. It uses purified DNA fragments from salmon that are processed into a product for injectable skin treatments.

Polynucleotides are used to support skin quality from within. The treatment focuses on hydration, elasticity, skin texture and processes involved in collagen production, among other things. Results develop gradually: your skin can look firmer, smoother and fresher without adding extra volume.

No. Fillers are used to add volume or support facial contours, among other things. Polynucleotides focus on improving skin quality and do not add comparable volume. Which treatment suits you best depends on your skin, wishes and the desired result.

Both treatments aim to improve the skin, but they work in different ways. With polynucleotides, a product is injected into the skin. With microneedling, fine needles create controlled micro-channels to stimulate the skin’s natural repair process. Which treatment suits you best depends on factors such as your skin condition and treatment goal.

Yes. Polynucleotides can be used on the thin, sensitive skin around the eyes. Within the Rejuran range, Rejuran I is a variant specifically designed for the eye area. The treatment can be used to improve skin quality, hydration and fine lines around the eyes. For dark circles, the doctor will first assess the cause, as not every type of dark discolouration can be treated in the same way.

The effect develops gradually. The first changes in hydration and skin quality often become visible after a few weeks. The final result is usually assessed after a full course of treatments. How quickly you notice a difference varies from person to person and depends on factors such as your skin condition and treatment plan.

At Amsterdam Skin Clinic, we usually recommend a course of around three treatments, with a few weeks between sessions. The exact number of treatments depends on your skin condition, treatment area and desired result. The doctor will create a personal treatment plan during the consultation.

The result is not permanent. After a course of treatments, the effect can remain visible for an average of around 6 to 12 months. This varies from person to person and depends on factors such as your skin condition, lifestyle, the number of treatments and any maintenance treatments.

At Amsterdam Skin Clinic, a polynucleotide treatment currently costs €350 per session. A treatment plan often consists of several sessions. During the consultation, the doctor will discuss how many treatments are recommended in your situation, so you know in advance what to expect.

As with any injectable treatment, side effects can occur. After the treatment, you may experience temporary redness, swelling, sensitivity, small bumps or minor bruising. Beforehand, the doctor will discuss your health, expectations and any risks, and assess whether the treatment is suitable for you.

In some cases, yes. Polynucleotides can be part of a broader treatment plan that includes, for example, microneedling or other skinboosters. Which combination and timing are appropriate depends on your skin, treatment goal and recovery period. A personal treatment plan can be created during the consultation.

Did you know?!

Did you know
Did you know that Rejuran not only focuses on hydration, but also supports processes in the skin involved in collagen and elasticity? As a result, your skin can gradually look firmer, smoother and more resilient, without adding extra volume.

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I had a HIFU treatment at Amsterdam Skin Clinic for my jawline and cheeks, because I noticed my face was starting to look a little less firm and I wanted a fresher, more lifted appearance. I was specifically looking for something with natural-looking results, without fillers or anything too invasive. I really liked the consultation. Everything was explained clearly and calmly, including how HIFU works and what kind of results I could realistically expect. The treatment itself was very manageable. You do feel it, but for me it was completely tolerable. I also appreciated that they checked in with me throughout the session to make sure I was comfortable. I’ve now had two treatments, and after a few months I started to notice a real difference. After around six months, my skin looks and feels firmer, and my jawline is more defined. My cheeks also seem slightly lifted, which gives my face a more refreshed look overall. The results are subtle, but definitely noticeable if you know your own face well. I’m planning to do one more treatment to maintain the results for longer. Overall, I’m really happy I chose HIFU at Amsterdam Skin Clinic, and I would definitely recommend it if you’re looking for a natural boost in lift and firmness.
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This is the best skin clinic in Amsterdam, I went here to get some Botox and micro needling the after product was amazing my skin has never looked better. The employees were so nice, welcoming and overall amazing, and I left with a bunch of products making my skin look amazing.
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This is the best skin clinic in Amsterdam, I went here to get some Botox and laser hair removal and the after product was amazing I look 10 years younger and my skin looks so good from the laser hair removal, the hair has not grown back yet and it’s been 4 weeks. The employees were so nice and welcoming and I left with a bunch of products making my skin look so glowy and soft, and my acne has gone down so much.
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Ik heb een ontzettend fijne ervaring gehad bij Amsterdam Skin Clinic. Vanaf het eerste moment voelde ik me welkom en op mijn gemak. De behandeling werd heel professioneel en met veel zorg gedaan, maar wat voor mij echt het grootste verschil maakte, was de persoonlijke aandacht. De arts nam echt de tijd voor me, luisterde goed en gaf niet alleen eerlijk en deskundig advies, maar was er ook emotioneel voor me op een moment dat ik dat echt nodig had. Dat raakte me oprecht. Ik ben ontzettend dankbaar en kan deze kliniek dan ook van harte aanbevelen.
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